Effect of osteoconductive hyaluronate hydrogels on calvarial bone regeneration
نویسندگان
چکیده
منابع مشابه
Effect of osteoconductive hyaluronate hydrogels on calvarial bone regeneration
BACKGROUND Without exploitation of possibly immunogenic and carcinogenic bone morphogenetic protein, we developed simple but clinically feasible artificial bone graft using osteoconductive hyaluronate (HA) hydrogels and bioactive MegaGen synthetic bone (MGSB). METHODS HA hydrogels were synthesized by the crosslinking reaction between carboxyl groups of HA and amine groups of gelatin (GEL). Th...
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A novel artificial bone substitute composed of bioactive MegaGen synthetic bone (MGSB) and hyaluronate (HA) hydrogels was successfully developed for bone tissue engineering applications. HA is known to play important roles in bone regeneration due to its angiogenic and osteoconductive characteristics. Accordingly, HA hydrogel was designed to supply HA continuously for effective bone regeneratio...
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ژورنال
عنوان ژورنال: Biomaterials Research
سال: 2014
ISSN: 2055-7124
DOI: 10.1186/2055-7124-18-8